FOXA1 anticorps (AA 270-320)

N° du produit ABIN6991829

L’anticorps Lapin Polyclonal anti-FOXA1 a été validé pour WB et ELISA. Il convient pour détecter FOXA1 dans des échantillons de Humain.

Aperçu rapide pour FOXA1 anticorps (AA 270-320) (ABIN6991829)

Antigène: FOXA1 (Forkhead Box A1 (FOXA1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXA1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-FOXA1 anticorps

Épitope: AA 270-320

Specificité: Multiple isoforms of FOXA1 exists as a result of alternative splicing event.

Purification: FOXA1 Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal FOXA1 antibody was raised against a 17 amino acid peptide near the center of human FOXA1. The immunogen is located within amino acids 270 - 320 of FOXA1.

Isotype: IgG

Information d'application

Indications d'application: FOXA1 antibody can be used for detection of FOXA1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: FOXA1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: FOXA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur FOXA1

Antigène: FOXA1 (Forkhead Box A1 (FOXA1))

Autre désignation: FOXA1

Sujet: FOXA1 Antibody: FOXA1 is one of three members of the FOXA family, a subset of the forkhead family of transcription factors which play vital roles in development. It has also been implicated in the development of a number of other organs including the androgen and estrogen regulated tissues of the breast and prostate. FOXA1 modulates the transcriptional activity of nuclear hormone receptors and regulates apoptosis by inhibiting the expression of BCL-2. It is an essential protein for the transcriptional activity of both androgen receptor (AR) and estrogen receptor-α, (ER). FOXA1 plays a pivotal role from early stage cancer through to drug resistant and metastatic disease. FOXA1 is not only an attractive therapeutic target but could potentially function as a novel biomarker.

Poids moléculaire: 52 kDa

ID gène: 3169

NCBI Accession: NP_004487

UniProt: P55317

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis